The Association for Long Term Existence & Resilience

Fostering ways to alter

the long-term trajectory of humanity

About Us

ALTER, the Association for Long Term Existence & Resilience, is an academic research and advocacy organization, based in Israel which works to investigate, demonstrate, and foster useful ways to improve the future in the short term, and to safeguard and improve the long-term trajectory of humanity

Our Work

Israel ranks among the top countries globally in percent of GDP spent on scientific research and development. Despite being the 100th largest country by population, Israel ranks 12th in the world for scientific output, the 5th largest technology ecosystem, and spends the highest percentage of all countries on science and technology GDP. As such, Israeli researchers, technology, and business play a large role in shaping the future globally. However, Israeli culture generally focuses on the ‘here-and-now.’ As such, it rarely engages in long term strategic thinking, especially not via a risk reduction lens. ALTER works to fill this gap.

ALTER seeks to capitalize on the rich resource pool that the country provides, collaborating with researchers, entrepreneurs, and policy makers to ensure the wellbeing of future generations and working to prevent, mitigate, and build resilience against potential threats to long-term wellbeing.

Our Areas of Focus


We work to build a community of researchers and practitioners that strive to build a better future via a risk reduction lens. We hold conferences and community building events as well as work to identify and nurture the careers of individuals with high capacity to make contributions to research and/or policy in global catastrophic risk (GCR) locally and globally.


We work to leverage the evidence base to provide decision-makers with the tools, knowledge, and support necessary to enact risk resilient policy and regulation. We engage with policy makers, hold round-tables, participate in global forums, and work to promote holistic, risk-reduction policies both in Israel and globally.


We conduct research, building the evidence base necessary to safeguard humanity's continued existence and resilience against potential threats. We conduct in-house research as well as in partnership with academia and thinktanks.

Our People

David Manheim
Founder, Director of Policy & Research
David is a public policy researcher specializing in biological and technological risks and the impacts of new technologies. He has done research on topics from COVID-19 to the future of pandemic response and monitoring to forecasting risks of AI at the World Bank, the Council on Strategic Risks, and Oxford’s Future of Humanity Institute. In addition to dozens of academic publications in journals ranging from Technological Forecasting and Social Change to Clinical Infectious Diseases, and from Health Security to PLoS Computational Biology, his work on the implications, risks, and management of novel technologies has appeared in Foreign Affairs and TechCrunch.

Asher Brass
Standards fellow

Asher is a researcher focused on artificial intelligence through a standards and cybersecurity lens. His work with ALTER is in conjunction with his work at the Institute for AI Policy and Strategy (IAPS) where he is a researcher on the compute governance team. Asher previously served as the Head of the Cyber Analysis Team at Cynerio, a medical device cybersecurity start-up. He also previously served as a cybersecurity officer in the Israeli Military Intelligence Directorate (Unit 8200) and was a Senior Technological Researcher at the Israeli Prime Minister’s Office. Asher has a BA in Political Science and International Relations from The Open University of Israel.
Naham Shapiro
Naham ensures that ALTER’s day to day runs smoothly. He also works on wide-ranging projects, especially those to which he can bring his public health expertise and background. Before joining ALTER, Naham worked building community health projects and primary care systems in India, Uganda, and Israel. He also conducted research on public health education and data-collection for planning municipal services. He holds a BA in Arabic Studies from the University of Maryland, College Park and a Masters of Public Health (MPH) from the Hebrew University.

Our Partners

University of Haifa I Technion - Israel Institute of Technology
Effective Altruism Israel
Transformative Futures Institute
Transformative Futures Institute

Institutional Memberships

We are proud to be institutional members in the US Artificial Intelligence Safety Consortium (AISIC) of the US National Institute of Standards and Technology as well as in the Pandemic Action Network.